3-(1-Hydroxyethyl)phenylboronic acid

3-(1-Hydroxyethyl)phenylboronic acid - Names and Identifiers

Name	[3-(1-hydroxyethyl)phenyl]boronic acid
Synonyms	3-(1-Hydroxyethyl)phenylboronic acid [3-(1-hydroxyethyl)phenyl]boronic acid Boronic acid, B-[3-(1-hydroxyethyl)phenyl]-
CAS	1036760-03-8
InChI	InChI=1S/C8H11BO3/c1-6(10)7-3-2-4-8(5-7)9(11)12/h2-6,10-12H,1H3

3-(1-Hydroxyethyl)phenylboronic acid - Physico-chemical Properties

Molecular Formula	C8H11BO3
Molar Mass	165.98
Density	1.20±0.1 g/cm3(Predicted)
Melting Point	98.2 °C(Solv: tetrahydrofuran (109-99-9))
Boling Point	361.0±44.0 °C(Predicted)
pKa	8.49±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

3-(1-Hydroxyethyl)phenylboronic acid - Introduction

3-(1-Hydroxyethyl) phenylboronic acid is an organoboron compound, also known as HEPBA(3-(Hydroxyethyl)phenylboronic acid). It has the following properties:

1. Appearance: 3-(1-hydroxyethyl) phenylboronic acid is a white crystalline powder.

2. Solubility: It is easy to dissolve in water and can also be dissolved in some organic solvents.

3. chemical properties: 3-(1-hydroxyethyl) phenylboronic acid can react with enol, aldehyde, ketone and other compounds to form a stable esterification product.

4. use: 3-(1-hydroxyethyl) phenyl boronic acid is an important organic synthesis intermediates. It is widely used in drug synthesis, coordination chemistry, catalyst design and other fields. For example, it can be used in the synthesis of fluorescent dyes, natural product synthesis, and the preparation of phenolic compounds.

5. preparation method: usually, 3-(1-hydroxyethyl) phenyl boric acid can be obtained by the reaction of boric acid with hydroxyethyl benzaldehyde, and then by dehydration reaction.

6. safety information: 3-(1-hydroxyethyl) phenyl boronic acid is a chemical, should comply with the safety practice. It is irritating to the skin, eyes and respiratory tract and needs to be rinsed with water after contact. Wear appropriate personal protective equipment during use to avoid inhalation of dust or contact with skin.

Last Update：2024-04-09 02:00:40